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Girl´s Day at the IIEG on April 28th, 2016
On April 28th, 2016 the IIEG is part of the initiative Girl´s Day. We are very happy to welcome 6 young girls and show them …
New paper published in Science about rare variant in SCARB1 raises HDL cholesterol and increases risk of coronary heart disease
Coronary heart disease is a tale of two forms of plasma cholesterol. In contrast to the well-established effects of “bad” cholesterol (LDL-C), the role of …
New paper published in NEJM about “Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease”
Through DNA genotyping using the Exome-Array, we tested 54,003 coding-sequence variants covering 13,715 human genes in up to 72,868 patients with CAD and 120,770 controls …
Most comprehensive genetic study for CAD in 185,000 cases and controls revealed novel insights in disease pathology
Members of the IIEG together with colleagues from the CARDIoGRAMplusC4D consortium published the most comprehensive genetic study for CAD. Existing knowledge of genetic variants affecting …
New study published in ATVB: Prediction of Causal Candidate Genes in Coronary Artery Disease Loci
Genome-wide association studies (GWAS) have to date identified 159 significant and suggestive loci for coronary artery disease (CAD). Almost all of these loci have been …
iPS-HL – a joint venture between the Institute of Neurogenetics and the IIEG
Christine Klein, Philip Seibler, Stephanie Stoelting, Anne Grünewald and Jeanette Erdmann, as future founders of iPS-HL, were awarded the Gründerpreis „BioMedTec 2014“ of the Sparkasse …
Genome research. Quo vadis, Germany?
Currently, all over the world large-scale projects aiming at sequencing thousands of probands get kicked-off, like the „precision medicine initiative“ in the US, the 100,000 …
Genetic research identifies novel pathway leading to myocardial infarction
Starting with a severely affected family, a research team led by Jeanette Erdmann, Christian Hengstenberg and Heribert Schunkert (Institut für Integrative und Experimentelle Genomik, University …
Shorter height is genetically associated with an increased risk of coronary artery disease
For long it is known that shorter adult height is associated with an increased risk of coronary artery disease. This association is mainly explained by …
Visit of the Prime Minister of Schleswig-Holstein at the IIEG
Thorsten Albig, the Prime Minister of Schleswig-Holstein, started his „Summer Tour“ at the University of Lübeck. He was interested to learn more about the members …
Novel mechanism identified by which ADAMTS-7 affects neointima formation.
In a collaborative study, mainly between Munich (Thorsten Kessler and Heribert Schunkert) and colleagues from the Department of Physiology and Pathophysiology in Beijing (Lu Zhang …