Christop Westenberger

Functional Genomics gets a major boost at the ICG

The Institute for Cardiogenetics at the University of Lübeck is thrilled to announce a major grant from the Corona-Stiftung. The fund is dedicated to supporting the innovative work of Dr. Redouane Aherrarhou, a trailblazing researcher who, under the mentorship of Prof. Jeanette Erdmann, will establish his independent junior research group to take a novel approach to understanding coronary artery disease (CAD). The research project, entitled “Dissecting Sex Differences in Coronary Artery Calcification with System Genetics”, aims to illuminate the complex genetic interplay behind coronary artery calcification (CAC) – a phenomenon strongly associated with CAD and fatal plaque rupture.

“Stem Cell Club Lübeck” on July 4, 2023 at 3:00pm

The Stem Cell Club Lübeck (SCCL) is a series of virtual research talks, hosted by Dr. Anja Trillhaase from the Institute for Cardiogenetics.

The SCCL aims to connect stem cell and organoid researchers across Germany, and in the northern areas in particular.

Especially, junior researchers are invited to join the meetings and connect with peers.

Every two months a virtual meeting will be held, where one invited external speaker and one internal speaker from Lübeck, Hamburg or Kiel will present and discuss their work with the audience.

This will be a great opportunity to further bring together research teams working on stem cells and organoids, to intensify the collaborative work and to give junior researchers the possibility to get in touch with different researchers in the field apart from big conferences.

The third Stem Cell Club Lübeck meeting will take place on July 4th 2023 at 3 pm!

Registration: https://zoom.us/meeting/register/tJ0pduCuqDwtHtHQ0IDOAVvQnT51dkUGgd2E

Physiological Reviews Podcasts

Genetic research, including genome-wide association studies (GWAS), plays an increasingly crucial role in studying the physiology and pathophysiology of cardiovascular disease. Deputy Editor Dr. Carol Ann Remme conducts an interview with authors Prof. Jeanette Erdmann (University of Lübeck, Germany) and Prof. Connie Bezzina (Amsterdam University Medical Center, Netherlands) about their latest Review published in Physiological Reviews by Walsh et al. GWAS focus on identifying genetic variations associated with specific traits, and it is imperative to investigate these variations to comprehend an individual’s susceptibility to particular diseases. Unraveling the genetic foundation of a disease can facilitate the discovery of therapeutic targets for clinical interventions. The experts delve into the application of GWAS in studying rare disorders like Brugada Syndrome, as well as common disorders such as myocardial infarction. The potential applications of GWAS are extensive, ranging from unveiling novel insights into the pathophysiology of cardiovascular disease to potentially developing clinically applicable polygenic risk scores in the future. Tune in to gain a deeper understanding of these topics.

https://physrev.podbean.com/e/genome-wide-association-studies-of-cardiovascular-disease/

Research.com

Research.com, a prominent academic platform for researchers, has recently published the 2023 Edition of their Ranking of Best Scientists in Genetics. We are thrilled to have been informed that Jeanette Erdmann has been ranked #397 in the world ranking and #21 in Germany. Additionally, she has been awarded the Genetics Leader Award for 2023. The ranking is based on the D-index metric, which considers only papers and citation values for the examined discipline. The ranking includes only leading scientists with a D-index of at least 40 for academic publications in Genetics. Congratulations!

A Look Back at the 10-Year Anniversary Event of the Institute for Cardiogenetics

On May 5 and 6, 2023, the Institute for Cardiogenetics (ICG) celebrated its 10-year anniversary with a special event held at the University of Lübeck [1]. The two-day event took place at the CBBM and BMF Building in Marie-Curie-Straße, 23562 Lübeck [3].

The 10-year anniversary event was a momentous occasion, looking back at the progress made in cardiovascular research over the past decade and discussing the future of the field. Attendees had the opportunity to listen to various speakers, engage in discussions, and network with fellow professionals and researchers.

Some highlights of the event included presentations by renowned experts in the field of cardiogenetics, panel discussions on the latest developments and research findings, and a showcase of the institute’s achievements over the past ten years.

We got quite positive feedback that the event was well-organized and attended by a diverse group of professionals, academics, and students in the field of cardiogenetics. The atmosphere was one of collaboration and a shared passion for advancing cardiovascular research.

All in all, we feel that the 10-year anniversary event of the Institute for Cardiogenetics was a resounding success. It provided a platform for professionals and researchers in the field to come together, share their knowledge, and discuss the future of cardiogenetics. We did not only celebrate the past achievements of the institute but also set the stage for further advancements in cardiovascular research.

The DZHK research platform: maximisation of scientific value by enabling access to health data and biological samples collected in cardiovascular clinical studies.

Hoffmann J, Hanß S, Kraus M, Schaller J, Schäfer C, Stahl D, Anker SD, Anton G, Bahls T, Blankenberg S, Blumentritt A, Boldt LH, Cordes S, Desch S, Doehner W, Dörr M, Edelmann F, Eitel I, Endres M, Engelhardt S, Erdmann J, Eulenburg K, Falk V, Felix SB, Frank D, Franke T, Frey N, Friede T, Geidel L, Germans L, Grabmaier U, Halle M, Hausleiter J, Jakobi V, Jebran AF, Jobs A, Kääb S, Karakas M, Katus HA, Klatt A, Knosalla C, Krebser J, Landmesser U, Lee M, Lehnert K, Lesser S, Leyh K, Lorbeer R, Mach-Kolb S, Meder B, Nagel E, Nolte CH, Parwani AS, Petersmann A, Puls M, Rau H, Reiser M, Rienhoff O, Scharfe T, Schattschneider M, Scheel H, Schnabel RB, Schuster A, Schmitt B, Seidler T, Seiffert M, Stähli BE, Stas A, J Stocker T, von Stülpnagel L, Thiele H, Wachter R, Wakili R, Weis T, Weitmann K, Wichmann HE, Wild P, Zeller T, Hoffmann W, Zeisberg EM, Zimmermann WH, Krefting D, Kühne T, Peters A, Hasenfuß G, Massberg S, Sommer T, Dimmeler S, Eschenhagen T, Nauck M.

Clin Res Cardiol. 2023 Mar 8. doi: 10.1007/s00392-023-02177-5.

https://pubmed.ncbi.nlm.nih.gov/36884078/

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