Raphael Betschart, MSc

•           Pre-processingand quality control of large-scale human short-read WGS data

•      Evaluation of secondary analysis pipelines with respect to accuracy and runtime

2021–ongoing

2021–ongoing

Bioinformatician at Cardio-CARE

2018–2021

Master of Science – Computational Biology & Bioinformatics, Joint Degree ETH Zurich, University of Zurich and University of Basel

2014–2018

Bachelor of Science – Biology, University of Zurich

1.      Betschart, R. O., Thiery, A., Aguilera-Garcia, D., Zoche, M., Moch, H., Twerenbold, R., Zeller, T., Blankenberg, S., &
Ziegler, A. (2022). Comparison of calling pipelines for whole genome sequencing: an empirical study demonstrating the importance of mapping and alignment. Sci Rep, 12, 21502. https://doi.org/10.1038/s41598-022-26181-3

2.     Betschart, R. O., Koliopanos, G., Garg, P., Guo, L., Rossi, M., Schönherr, S., Blankenberg, S., Twerenbold, R., Zeller, T., &
Ziegler, A. (2024). Comprehensive Analysis of the Genetic Variation in the LPA Gene from Short-Read Sequencing. Biomed, 4, 156–170. https://doi.org/10.3390/biomed4020013

3.     Betschart, R. O., Riccio, C., Aguilera-Garcia, D., Blankenberg, S., Guo, L., Moch, H., Seidl, D., Solleder, H., Thalen, F.,
Thiery, A., Twerenbold, R., Zeller, T., Zoche, M., & Ziegler, A. (2024). Biostatistical Aspects of Whole Genome Sequencing Studies: Preprocessing and Quality Control. Biom J, 66, e202300278. https://doi.org/10.1002/bimj.202300278

4.     Betschart, R. O., Thalen, F., Blankenberg, S., Zoche, M., Zeller, T., & Ziegler, A. (2025). A benchmark study of compression software for
human short-read sequence data. Sci Rep, 15, 15358. https://doi.org/10.1038/s41598-025-00491-8