Dr. rer. nat. Amer Ghalawinji
- Post doc
- +49 451 – 3101 8320
- Room: 067.000.10.031.00
- ilyas.ahmad@uni-luebeck.de
- ORCID iD: 0000-0003-4845-9227
- Twitter: iahmad_khan
To identify disease-causing rare variants in families in which cardiovascular disease (CVD) and congenital heart defect (CHD) appear as a heritable trait
Bioinformatical analysis of NGS data (whole exome)
Functional validation of novel candidate gene variants in CVDs
2018-ongoing
Senior research fellow, Institute for Cardiogenetics, University of Lübeck, Germany.
2016-2018
Postdoc, Institute for Cardiogenetics, University of Lübeck, Germany.
2015-2016
Postdoc, Cologne Center for Genomics (CCG) and Center for Biochemistry, University of Cologne, Germany.
2011-2015
Doctoral degree (Dr. rer. nat.), Cologne Center for Genomics (CCG) and Center for Biochemistry, University of Cologne Germany.
2009-2011
Research Associate at Human Molecular Genetics Lab, National Institute for Biotechnology and Genetic Engineering (NIBGE), Faisalabad, Pakistan.
2006-2008
Master of Science in Biotechnology (M.Phil.), NIBGE Faisalabad and Quaid-I-Azam University. Islamabad, Pakistan.
2001-2006
Bachelor of Science in Biotechnology, Bs (Hons) University of Malakand, Pakistan.
- DZHK
- European Society of Human Genetics (ESHG)
- Precision Medicine in Chronic Inflammation
- Prof. Shahid M. Baig (National Institute for Biotechnology and Genetic Engineering (NIBGE), Faisalabad, Pakistan)
- Prof. Peter Nürnberg (Cologne Center for Genomics (CCG), Cologne, Germany)
- Prof. Syed Zahid Jamal (National Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan)
Ramzan S, Tennstedt S, Tariq M, Khan S, Ul Ayan HN, Ali A, Munz M, Thiele H, Korejo AA, Mughal AR, Jamal SZ, Nürnberg P, Baig SM, Erdmann J, Ahmad I. A novel missense mutation in TNNI3K causes recessively inherited cardiac conduction disease in a consanguineous Pakistani family. Genes 2021, 12(8), 1282. https://doi.org/10.3390/genes12081282
Sukumaran SK, Stumpf M, Salamon S, Ahmad I, Bhattacharya K, Fischer S, Müller R, Altmüller J, Budde B, Thiele H, Tariq M, Malik NA, Nürnberg P, Baig SM, Hussain MS, Noegel AA. CDK5RAP2 interaction with components of the Hippo signaling pathway may play a role in primary microcephaly. Mol Genet Genomics. 2017 292(2):365-383. doi:10.1007/s00438-016-1277-x.
Martin CA, Ahmad I, Klingseisen A, Hussain MS, Bicknell LS, Leitch A, Nürnberg G, Toliat MR, Murray JE, Hunt D, Khan F, Ali Z, Tinschert S, Ding J, Keith C, Harley ME, Heyn P, Müller R, Hoffmann I, Cormier-Daire V, Dollfus H, Dupuis L, Bashamboo A, McElreavey K, Kariminejad A, Mendoza-Londono R, Moore AT, Saggar A, Schlechter C, Weleber R, Thiele H, Altmüller J, Höhne W, Hurles ME, Noegel AA, Baig SM, Nürnberg P, Jackson AP. Mutations in PLK4, encoding a master regulator of centriole biogenesis, cause microcephaly, growth failure and retinopathy. Nat Genet. 2014 Dec;46(12):1283-1292. doi:10.1038/ng.3122.
Hussain MS, Baig SM, Neumann S, Nürnberg G, Farooq M, Ahmad I, Alef T, Hennies HC, Technau M, Altmüller J, Frommolt P, Thiele H, Noegel AA, Nürnberg P. A truncating mutation of CEP135 causes primary microcephaly and disturbed centrosomal function. Am J Hum Genet. 2012 May 4;90(5):871-8. doi:10.1016/j.ajhg.2012.03.016.
Baig SM, Koschak A, Lieb A, Gebhart M, Dafinger C, Nürnberg G, Ali A, Ahmad I, Sinnegger-Brauns MJ, Brandt N, Engel J, Mangoni ME, Farooq M, Khan HU, Nürnberg P, Striessnig J, Bolz HJ: Loss of Ca(v)1.3 (CACNA1D) function in a human channelopathy with bradycardia and congenital deafness. Nat Neurosci. 2011 Jan; doi:10.1038/nn.2694.