Dr. rer. nat. Ilyas Ahmad

  • To identify disease-causing rare variants in families in which cardiovascular disease (CVD) and congenital heart defect (CHD) appear as a heritable trait

  • Bioinformatical analysis of NGS data (whole exome)

  • Functional validation of novel candidate gene variants in CVDs


Senior research fellow, Institute for Cardiogenetics, University of Lübeck, Germany.


Postdoc, Institute for Cardiogenetics, University of Lübeck, Germany.


Postdoc, Cologne Center for Genomics (CCG) and Center for Biochemistry, University of Cologne, Germany.


Doctoral degree (Dr. rer. nat.), Cologne Center for Genomics (CCG) and Center for Biochemistry, University of Cologne Germany.


Research Associate at Human Molecular Genetics Lab, National Institute for Biotechnology and Genetic Engineering (NIBGE), Faisalabad, Pakistan.


Master of Science in Biotechnology (M.Phil.), NIBGE Faisalabad and Quaid-I-Azam University. Islamabad, Pakistan.


Bachelor of Science in Biotechnology, Bs (Hons) University of Malakand, Pakistan.

  • DZHK
  • European Society of Human Genetics (ESHG)
  • Precision Medicine in Chronic Inflammation
  • Prof. Shahid M. Baig (National Institute for Biotechnology and Genetic Engineering (NIBGE), Faisalabad, Pakistan)
  • Prof. Peter Nürnberg (Cologne Center for Genomics (CCG), Cologne, Germany)
  • Prof. Syed Zahid Jamal (National Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan)
  1. Ahmad I, Baig SM, Abdulkareem AR, Hussain MS, Sur I, Toliat MR, Nürnberg G, Dalibor N, Moawia A, Waseem SS, Asif M, Nagra H, Sher M, Khan MMA, Hassan I, Rehman SU, Thiele H, Altmüller J, Noegel AA, Nürnberg P. Genetic heterogeneity in Pakistani microcephaly families revisited. Clin Genet. 2017 Jul;92(1):62-68. doi:10.1111/cge.12955.

  2. Sukumaran SK, Stumpf M, Salamon S, Ahmad I, Bhattacharya K, Fischer S, Müller R, Altmüller J, Budde B, Thiele H, Tariq M, Malik NA, Nürnberg P, Baig SM, Hussain MS, Noegel AA. CDK5RAP2 interaction with components of the Hippo signaling pathway may play a role in primary microcephaly. Mol Genet Genomics. 2017 292(2):365-383. doi:10.1007/s00438-016-1277-x.

  3. Martin CA, Ahmad I, Klingseisen A, Hussain MS, Bicknell LS, Leitch A, Nürnberg G, Toliat MR, Murray JE, Hunt D, Khan F, Ali Z, Tinschert S, Ding J, Keith C, Harley ME, Heyn P, Müller R, Hoffmann I, Cormier-Daire V, Dollfus H, Dupuis L, Bashamboo A, McElreavey K, Kariminejad A, Mendoza-Londono R, Moore AT, Saggar A, Schlechter C, Weleber R, Thiele H, Altmüller J, Höhne W, Hurles ME, Noegel AA, Baig SM, Nürnberg P, Jackson AP. Mutations in PLK4, encoding a master regulator of centriole biogenesis, cause microcephaly, growth failure and retinopathy. Nat Genet. 2014 Dec;46(12):1283-1292. doi:10.1038/ng.3122.

  4. Hussain MS, Baig SM, Neumann S, Nürnberg G, Farooq M, Ahmad I, Alef T, Hennies HC, Technau M, Altmüller J, Frommolt P, Thiele H, Noegel AA, Nürnberg P. A truncating mutation of CEP135 causes primary microcephaly and disturbed centrosomal function. Am J Hum Genet. 2012 May 4;90(5):871-8. doi:10.1016/j.ajhg.2012.03.016.

  5. Baig SM, Koschak A, Lieb A, Gebhart M, Dafinger C, Nürnberg G, Ali A, Ahmad I, Sinnegger-Brauns MJ, Brandt N, Engel J, Mangoni ME, Farooq M, Khan HU, Nürnberg P, Striessnig J, Bolz HJ: Loss of Ca(v)1.3 (CACNA1D) function in a human channelopathy with bradycardia and congenital deafness. Nat Neurosci. 2011 Jan; doi:10.1038/nn.2694.

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