Genetic variation at chromosome 1p13.3 affects sortilin mRNA expression, cellular LDL-uptake and serum LDL levels which translates to the risk of coronary artery disease

Linsel-Nitschke, P., Heeren, J., Aherrahrou, Z., Bruse, P., Gieger, C., Illig, T., Prokisch, H., Heim, K., Doering, A., Peters, A., Meitinger, T., Wichmann, H. E., Hinney, A., Reinehr, T., Roth, C., Ortlepp, J. R., Soufi, M., Sattler, A. M., Schaefer, J., Stark, K., Hengstenberg, C., Schaefer, A., Schreiber, S., Kronenberg, F., Samani, N. J., Schunkert, H., Erdmann, J.

Atherosclerosis. 2010 Jan;208(1):183-9. doi: 10.1016/j.atherosclerosis.2009.06.034. Epub 2009 Jul 8.

http://www.ncbi.nlm.nih.gov/pubmed/19660754

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