Sci Rep

CYP17A1 deficient XY mice display susceptibility to atherosclerosis, altered lipidomic profile and atypical sex development.

Aherrahrou R, Kulle AE, Alenina N, Werner R, Vens-Cappell S, Bader M, Schunkert H, Erdmann J, Aherrahrou Z.

Sci Rep. 2020 May 29;10(1):8792. doi: 10.1038/s41598-020-65601-0.

https://pubmed.ncbi.nlm.nih.gov/32472014/

CYP17A1 deficient XY mice display susceptibility to atherosclerosis, altered lipidomic profile and atypical sex development. Read More »

Genome-wide association meta-analysis of coronary artery disease and periodontitis reveals a novel shared risk locus.

Munz M, Richter GM, Loos BG, Jepsen S, Divaris K, Offenbacher S, Teumer A, Holtfreter B, Kocher T, Bruckmann C, Jockel-Schneider Y, Graetz C, Munoz L, Bhandari A, Tennstedt S, Staufenbiel I, van der Velde N, Uitterlinden AG, de Groot LCPGM, Wellmann J, Berger K, Krone B, Hoffmann P, Laudes M, Lieb W, Franke A, Dommisch H, Erdmann J, Schaefer AS.

Sci Rep. 2018 Sep 12;8(1):13678. doi: 10.1038/s41598-018-31980-8.

https://www.ncbi.nlm.nih.gov/pubmed/30209331

Genome-wide association meta-analysis of coronary artery disease and periodontitis reveals a novel shared risk locus. Read More »

Network analysis of coronary artery disease risk genes elucidates disease mechanisms and druggable targets.

Lempiäinen H, Brænne I, Michoel T, Tragante V, Vilne B, Webb TR, Kyriakou T, Eichner J, Zeng L, Willenborg C, Franzen O, Ruusalepp A, Goel A, van der Laan SW, Biegert C, Hamby S, Talukdar HA, Foroughi Asl H; CVgenes@target consortium, Pasterkamp G, Watkins H, Samani NJ, Wittenberger T, Erdmann J, Schunkert H, Asselbergs FW, Björkegren JLM.

Sci Rep. 2018 Feb 21;8(1):3434. doi: 10.1038/s41598-018-20721-6.

https://www.ncbi.nlm.nih.gov/pubmed/29467471

Network analysis of coronary artery disease risk genes elucidates disease mechanisms and druggable targets. Read More »

No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis

Loley C, Alver M, Assimes TL, Bjonnes A, Goel A, Gustafsson S, Hernesniemi J, Hopewell JC, Kanoni S, Kleber ME, Lau KW, Lu Y, Lyytikäinen LP, Nelson CP, Nikpay M, Qu L, Salfati E, Scholz M, Tukiainen T, Willenborg C, Won HH, Zeng L, Zhang W, Anand SS, Beutner F, Bottinger EP, Clarke R, Dedoussis G, Do R, Esko T, Eskola M, Farrall M, Gauguier D, Giedraitis V, Granger CB, Hall AS, Hamsten A, Hazen SL, Huang J, Kähönen M, Kyriakou T, Laaksonen R, Lind L, Lindgren C, Magnusson PK, Marouli E, Mihailov E, Morris AP, Nikus K, Pedersen N, Rallidis L, Salomaa V, Shah SH, Stewart AF, Thompson JR, Zalloua PA, Chambers JC, Collins R, Ingelsson E, Iribarren C, Karhunen PJ, Kooner JS, Lehtimäki T, Loos RJ, März W, McPherson R, Metspalu A, Reilly MP, Ripatti S, Sanghera DK, Thiery J, Watkins H, Deloukas P, Kathiresan S, Samani NJ, Schunkert H, Erdmann J, König IR.

Sci Rep. 2016 Oct 12;6:35278. doi: 10.1038/srep35278.

https://www.ncbi.nlm.nih.gov/pubmed/27731410

No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis Read More »

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