PLoS One

Genomic correlates of glatiramer acetate adverse cardiovascular effects lead to a novel locus mediating coronary risk

Brænne I, Zeng L, Willenborg C, Tragante V, Kessler T; CARDIoGRAM Consortium; CARDIoGRAMplusC4D Consortium, Willer CJ, Laakso M, Wallentin L, Franks PW, Salomaa V, Dehghan A, Meitinger T, Samani NJ, Asselbergs FW, Erdmann J, Schunkert.

PLoS One. 2017 Aug 22;12(8):e0182999. doi: 10.1371/journal.pone.0182999. eCollection 2017.

https://www.ncbi.nlm.nih.gov/pubmed/28829817

Genomic correlates of glatiramer acetate adverse cardiovascular effects lead to a novel locus mediating coronary risk Read More »

Powerful identification of cis-regulatory SNPs in human primary monocytes using allele-specific gene expression

Almlof, J. C., Lundmark, P., Lundmark, A., Ge, B., Maouche, S., Goring, H. H., Liljedahl, U., Enstrom, C., Brocheton, J., Proust, C., Godefroy, T., Sambrook, J. G., Jolley, J., Crisp-Hihn, A., Foad, N., Lloyd-Jones, H., Stephens, J., Gwilliam, R., Rice, C. M., Hengstenberg, C., Samani, N. J., Erdmann, J., Schunkert, H., Pastinen, T., Deloukas, P., Goodall, A. H., Ouwehand, W. H., Cambien, F., Syvanen, A. C.

PLoS One. 2012;7(12):e52260. doi: 10.1371/journal.pone.0052260. Epub 2012 Dec 26.

http://www.ncbi.nlm.nih.gov/pubmed/23300628

Powerful identification of cis-regulatory SNPs in human primary monocytes using allele-specific gene expression Read More »

Comprehensive exploration of the effects of miRNA SNPs on monocyte gene expression

Greliche, N., Zeller, T., Wild, P. S., Rotival, M., Schillert, A., Ziegler, A., Deloukas, P., Erdmann, J., Hengstenberg, C., Ouwehand, W. H., Samani, N. J., Schunkert, H., Munzel, T., Lackner, K. J., Cambien, F., Goodall, A. H., Tiret, L., Blankenberg, S., Tregouet, D. A., Cardiogenics, Consortium

PLoS One. 2012;7(9):e45863. doi: 10.1371/journal.pone.0045863. Epub 2012 Sep 21.

http://www.ncbi.nlm.nih.gov/pubmed/23029284

Comprehensive exploration of the effects of miRNA SNPs on monocyte gene expression Read More »

Genetic markers enhance coronary risk prediction in men: the MORGAM prospective cohorts

Hughes, M. F., Saarela, O., Stritzke, J., Kee, F., Silander, K., Klopp, N., Kontto, J., Karvanen, J., Willenborg, C., Salomaa, V., Virtamo, J., Amouyel, P., Arveiler, D., Ferrieres, J., Wiklund, P. G., Baumert, J., Thorand, B., Diemert, P., Tregouet, D. A., Hengstenberg, C., Peters, A., Evans, A., Koenig, W., Erdmann, J., Samani, N. J., Kuulasmaa, K., Schunkert, H.

PLoS One. 2012;7(7):e40922. doi: 10.1371/journal.pone.0040922. Epub 2012 Jul 25.

http://www.ncbi.nlm.nih.gov/pubmed/22848412

Genetic markers enhance coronary risk prediction in men: the MORGAM prospective cohorts Read More »

RANTES/CCL5 and risk for coronary events: results from the MONICA/KORA Augsburg case-cohort, Athero-Express and CARDIoGRAM studie

Herder, C., Peeters, W., Illig, T., Baumert, J., de Kleijn, D. P., Moll, F. L., Poschen, U., Klopp, N., Muller-Nurasyid, M., Roden, M., Preuss, M., Consortium, C. ARDIoGRAM, Karakas, M., Meisinger, C., Thorand, B., Pasterkamp, G., Koenig, W., Assimes, T. L., Deloukas, P., Erdmann, J., Holm, H., Kathiresan, S., Konig, I. R., McPherson, R., Reilly, M. P., Roberts, R., Samani, N. J., Schunkert, H., Stewart, A. F.

PLoS One. 2011;6(12):e25734. doi: 10.1371/journal.pone.0025734. Epub 2011 Dec 6.

http://www.ncbi.nlm.nih.gov/pubmed/22162987

RANTES/CCL5 and risk for coronary events: results from the MONICA/KORA Augsburg case-cohort, Athero-Express and CARDIoGRAM studie Read More »

Large-scale gene-centric analysis identifies novel variants for coronary artery disease

Butterworth AS, Braund PS, Farrall M, Hardwick RJ, Saleheen D, Peden JF, Soranzo N, Chambers JC, Sivapalaratnam S, Kleber ME, Keating B, Qasim A, Klopp N, Erdmann J, Assimes TL, Ball SG, Balmforth AJ, Barnes TA, Basart H, Baumert J, Bezzina CR, Boerwinkle E, Boehm BO, Brocheton J, Bugert P, Cambien F, Clarke R, Codd V, Collins R, Couper D, Cupples LA, de Jong JS, Diemert P, Ejebe K, Elbers CC, Elliott P, Fornage M, Franzosi MG, Frossard P, Garner S, Goel A, Goodall AH, Hengstenberg C, Hunt SE, Kastelein JJ, Klungel OH, Klüter H, Koch K, König IR, Kooner AS, Laaksonen R, Lathrop M, Li M, Liu K, McPherson R, Musameh MD, Musani S, Nelson CP, O’Donnell CJ, Ongen H, Papanicolaou G, Peters A, Peters BJ, Potter S, Psaty BM, Qu L, Rader DJ, Rasheed A, Rice C, Scott J, Seedorf U, Sehmi JS, Sotoodehnia N, Stark K, Stephens J, van der Schoot CE, van der Schouw YT, Thorsteinsdottir U, Tomaszewski M, van der Harst P, Vasan RS, Wilde AA, Willenborg C, Winkelmann BR, Zaidi M, Zhang W, Ziegler A, de Bakker PI, Koenig W, Mätz W, Trip MD, Reilly MP, Kathiresan S, Schunkert H, Hamsten A, Hall AS, Kooner JS, Thompson SG, Thompson JR, Deloukas P, Ouwehand WH, Watkins H, Danesh J, Samani NJ, Barnes T, Rafelt S, Codd V, Tomaszewski M, Ouwehand WH, Bruinsma N, Dekker LR, Henriques JP, Koch KT, de Winter RJ, Alings M, Allaart CF, Gorgels AP, Verheugt FW, Braund PS, Thompson JR, Samani NJ, Mueller M, Meisinger C, DerOhannessian S, Mehta NN, Ferguson J, Hakonarson H, Matthai W, Wilensky R, Hopewell JC, Parish S, Linksted P, Notman J, Gonzalez H, Young A, Ostley T, Munday A, Goodwin N, Verdon V, Shah S, Cobb L, Edwards C, Mathews C, Gunter R, Benham J, Davies C, Cobb M, Cobb L, Crowther J, Richards A, Silver M, Tochlin S, Mozley S, Clark S, Radley M, Kourellias K, Silveira A, Söderholm B, Olsson P, Barlera S, Tognoni G, Rust S, Assmann G, Heath S, Zelenika D, Gut I, Green F, Farrall M, Peden J, Goel A, Ongen H, Franzosi MG, Lathrop M, Seedorf U, Clarke R, Collins R, Hamsten A, Watkins H, Aly A, Anner K, Björklund K, Blomgren G, Cederschiöld B, Danell-Toverud K, Eriksson P, Grundstedt U, Hamsten A, Heinonen M, Hellénius ML, van’t Hooft F, Husman K, Lagercrantz J, Larsson A, Larsson M, Mossfeldt M, Mälarstig A, Olsson G, Sabater-Lleal M, Sennblad B, Silveira A, Strawbridge R, Söderholm B, Öhrvik J, Zaman KS, Mallick NH, Azhar M, Samad A, Ishaq M, Shah N, Samuel M, Schunkert H, König IR, Kathiresan S, Reilly M, Assimes TL, Holm H, Preuss M, Stewart AF, Barbalic M, Gieger C, Absher D, Aherrahrou Z, Allayee H, Altshuler D, Anand S, Andersen K, Anderson JL, Ardissino D, Ball SG, Balmforth AJ, Barnes TA, Becker LC, Becker DM, Berger K, Bis JC, Boekholdt SM, Boerwinkle E, Braund PS, Brown MJ, Burnett MS, Buysschaert I, Carlquist JF, Chen L, Codd V, Davies RW, Dedoussis G, Dehghan A, Demissie S, Devaney J, Do R, Doering A, El Mokhtari NE, Ellis SG, Elosua R, Engert JC, Epstein S, de Faire U, Fischer M, Folsom AR, Freyer J, Gigante B, Girelli D, Gretarsdottir S, Gudnason V, Gulcher JR, Tennstedt S, Halperin E, Hammond N, Hazen SL, Hofman A, Horne BD, Illig T, Iribarren C, Jones GT, Jukema JW, Kaiser MA, Kaplan LM, Kastelein JJ, Khaw KT, Knowles JW, Kolovou G, Kong A, Laaksonen R, Lambrechts D, Leander K, Li M, Lieb W, Diemert P, Lettre G, Loley C, Lotery AJ, Mannucci PM, Maouche S, Martinelli N, McKeown PP, Meisinger C, Meitinger T, Melander O, Merlini PA, Mooser V, Morgan T, Mühleisen TW, Muhlestein JB, Musunuru K, Nahrstaedt J, Nelson CP, Nöthen MM, Olivieri O, Peyvandi F, Patel RS, Patterson CC, Peters A, Qu L, Quyyumi AA, Rader DJ, Rallidis LS, Rice C, Rosendaal FR, Rubin D, Salomaa V, Sampietro ML, Sandhu MS, Schadt E, Schäfer A, Schillert A, Schreiber S, Schrezenmeir J, Schwartz SM, Siscovick DS, Sivananthan M, Sivapalaratnam S, Smith AV, Smith TB, Snoep JD, Soranzo N, Spertus JA, Stark K, Stefansson K, Stirrups K, Stoll M, Tang WH, Thorgeirsson G, Thorleifsson G, Tomaszewski M, Uitterlinden AG, van Rij AM, Voight BF, Wareham NJ, AWells G, Wichmann HE, Willenborg C, Witteman JC, Wright BJ, Ye S, Ziegler A, Cambien F, Goodall AH, Cupples LA, Quertermous T, März W, Hengstenberg C, Blankenberg S, Ouwehand WH, Hall AS, Deloukas P, Thorsteinsdottir U, Roberts R, Thompson JR, O’Donnell CJ, McPherson R, Erdmann J, Samani NJ, Onland-Moret NC, van Setten J, de Bakker PI, Verschuren WM, Boer JM, Wijmenga C, Hofker MH, Maitland-van der Zee AH, de Boer A, Grobbee DE, Attwood T, Belz S, Braund P, Cambien F, Cooper J, Crisp-Hihn A, Diemert P, Deloukas P, Foad N, Erdmann J, Goodall AH, Gracey J, Gray E, Gwilliams R, Heimerl S, Hengstenberg C, Jolley J, Krishnan U, Lloyd-Jones H, Lugauer I, Lundmark P, Maouche S, Moore JS, Muir D, Murray E, Nelson CP, Neudert J, Niblett D, O’Leary K, Ouwehand WH, Pollard H, Rankin A, Rice CM, Sager H, Samani NJ, Sambrook J, Schmitz G, Scholz M, Schroeder L, Schunkert H, Syvannen AC, Tennstedt S, Wallace C.

PLoS Genet. 2011 Sep;7(9):e1002260. doi: 10.1371/journal.pgen.1002260. Epub 2011 Sep 22.

https://www.ncbi.nlm.nih.gov/pubmed/21966275

Large-scale gene-centric analysis identifies novel variants for coronary artery disease Read More »

Common polymorphisms influencing serum uric acid levels contribute to susceptibility to gout, but not to coronary artery disease

Stark, K., Reinhard, W., Grassl, M., Erdmann, J., Schunkert, H., Illig, T., Hengstenberg, C.

PLoS One. 2009 Nov 5;4(11):e7729. doi: 10.1371/journal.pone.0007729.

http://www.ncbi.nlm.nih.gov/pubmed/19890391

Common polymorphisms influencing serum uric acid levels contribute to susceptibility to gout, but not to coronary artery disease Read More »

Lifelong reduction of LDL-cholesterol related to a common variant in the LDL-receptor gene decreases the risk of coronary artery disease–a Mendelian Randomisation study

Linsel-Nitschke, P., Gotz, A., Erdmann, J., Braenne, I., Braund, P., Hengstenberg, C., Stark, K., Fischer, M., Schreiber, S., El Mokhtari, N. E., Schaefer, A., Schrezenmeir, J., Rubin, D., Hinney, A., Reinehr, T., Roth, C., Ortlepp, J., Hanrath, P., Hall, A. S., Mangino, M., Lieb, W., Lamina, C., Heid, I. M., Doering, A., Gieger, C., Peters, A., Meitinger, T., Wichmann, H. E., Konig, I. R., Ziegler, A., Kronenberg, F., Samani, N. J., Schunkert, H., Wellcome Trust Case Control, Consortium, Cardiogenics, Consortium

PLoS One. 2008 Aug 20;3(8):e2986. doi: 10.1371/journal.pone.0002986.

http://www.ncbi.nlm.nih.gov/pubmed/18714375

Lifelong reduction of LDL-cholesterol related to a common variant in the LDL-receptor gene decreases the risk of coronary artery disease–a Mendelian Randomisation study Read More »

Association of common polymorphisms in GLUT9 gene with gout but not with coronary artery disease in a large case-control study

Stark, K., Reinhard, W., Neureuther, K., Wiedmann, S., Sedlacek, K., Baessler, A., Fischer, M., Weber, S., Kaess, B., Erdmann, J., Schunkert, H., Hengstenberg, C.

PLoS One. 2008 Apr 9;3(4):e1948. doi: 10.1371/journal.pone.0001948.

http://www.ncbi.nlm.nih.gov/pubmed/18398472

Association of common polymorphisms in GLUT9 gene with gout but not with coronary artery disease in a large case-control study Read More »

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